Zhicheng Ji Lab, Duke University School of Medicine

About PI

Zhicheng Ji

Dr. Zhicheng Ji is a tenure-track Assistant Professor in the Department of Biostatistics and Bioinformatics at Duke University School of Medicine. He obtained his Ph.D. in Biostatistics and M.S.E. in Computer Science from Johns Hopkins University in 2020. His research focuses on artificial intelligence and statistical modeling for single-cell genomics, spatial genomics, and biomedical imaging.

Team

Research

Large language model–driven methods for biomedical data science

Assessing GPT-4 for cell type annotation in single-cell RNA-seq analysis. 2024. Nature Methods
Comparing large language models and human programmers for generating programming code. 2025. Advanced Science

Methods for analyzing spatial transcriptomics data and biomedical imaging

Vispro improves imaging analysis for Visium spatial transcriptomics. 2025. Genome Biology
GeneSegNet: a deep learning framework for cell segmentation by integrating gene expression and imaging. 2023. Genome Biology

Methods for studying cellular senescence and human aging.

Single-cell and spatial detection of senescent cells using DeepScence. 2025. Cell Genomics (In press)

Teaching

BIOSTAT 824 – Case Studies in Biomedical Data Science (2025). Course Link